Journal: medRxiv
Article Title: A 3’UTR Insertion Is a Candidate Causal Variant at the TMEM106B Locus Associated with Increased Risk for FTLD-TDP
doi: 10.1101/2023.07.06.23292312
Figure Lengend Snippet: Effect of rs1990622 as a TMEM106B expression quantitative trait locus (eQTL) or protein quantitative trait locus (pQTL). All effect sizes are reported for the tested A allele with the G allele set as reference at rs1990622. Parameter estimates are those reported by respective studies and may be on different scales given different normalization procedures for transcriptomic and proteomic data.
Article Snippet: In a smaller brain eQTL dataset (African ancestry - Metabrain; n=1,016), rs1990622(A) was significantly associated with increased TMEM106B expression.
Techniques: Expressing, Clinical Proteomics